Detalhe da pesquisa
1.
ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
Mol Cell
; 81(1): 88-103.e6, 2021 01 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33220178
2.
HCV IRES Captures an Actively Translating 80S Ribosome.
Mol Cell
; 74(6): 1205-1214.e8, 2019 06 20.
Artigo
Inglês
| MEDLINE | ID: mdl-31080011
3.
The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA.
Mol Cell
; 73(4): 738-748.e9, 2019 02 21.
Artigo
Inglês
| MEDLINE | ID: mdl-30595437
4.
Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Nat Chem Biol
; 20(5): 605-614, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38267667
5.
Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers.
Proc Natl Acad Sci U S A
; 119(9)2022 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35197289
6.
Protection of eIF2B from inhibitory phosphorylated eIF2: A viral strategy to maintain mRNA translation during the PKR-triggered integrated stress response.
J Biol Chem
; 299(11): 105287, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37742919
7.
Nondomain biopolymers: Flexible molecular strategies to acquire biological functions.
Genes Cells
; 28(8): 539-552, 2023 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-37249032
8.
The landscape of translational stall sites in bacteria revealed by monosome and disome profiling.
RNA
; 28(3): 290-302, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34906996
9.
Crystal structure of eukaryotic translation initiation factor 2B.
Nature
; 531(7592): 122-5, 2016 Mar 03.
Artigo
Inglês
| MEDLINE | ID: mdl-26901872
10.
Incorporation of Halogenated Amino Acids into Antibody Fragments at Multiple Specific Sites Enhances Antigen Binding.
Chembiochem
; 22(1): 120-123, 2021 01 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32815262
11.
Switching on stress.
Nat Chem Biol
; 20(4): 394-395, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-37945895
12.
eIF2B and the Integrated Stress Response: A Structural and Mechanistic View.
Biochemistry
; 59(13): 1299-1308, 2020 04 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32200625
13.
Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model.
J Neurochem
; 154(1): 25-40, 2020 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31587290
14.
Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.
Proc Natl Acad Sci U S A
; 112(31): E4197-205, 2015 Aug 04.
Artigo
Inglês
| MEDLINE | ID: mdl-26183229
15.
Expression, purification, and crystallization of Schizosaccharomyces pombe eIF2B.
J Struct Funct Genomics
; 17(1): 33-8, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-27023709
16.
Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions.
Nature
; 467(7315): 612-6, 2010 Sep 30.
Artigo
Inglês
| MEDLINE | ID: mdl-20882017
17.
Crystal Structure of Okadaic Acid Binding Protein 2.1: A Sponge Protein Implicated in Cytotoxin Accumulation.
Chembiochem
; 16(10): 1435-9, 2015 Jul 06.
Artigo
Inglês
| MEDLINE | ID: mdl-25965326
18.
Controlling the fluorescence of benzofuran-modified uracil residues in oligonucleotides by triple-helix formation.
Chembiochem
; 16(1): 167-76, 2015 Jan 02.
Artigo
Inglês
| MEDLINE | ID: mdl-25469677
19.
Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
Proc Natl Acad Sci U S A
; 109(9): 3305-10, 2012 Feb 28.
Artigo
Inglês
| MEDLINE | ID: mdl-22331897
20.
Crystal structure of the eukaryotic translation initiation factor 2A from Schizosaccharomyces pombe.
J Struct Funct Genomics
; 15(3): 125-30, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24569939